一、个人简介

肖旭，副教授，厦门大学计算机科学与技术博士，2016年获得华东理工大学生物工程学士学位，2018年获得比利时鲁汶大学生物信息硕士学位。主要研究方向为单细胞影像和肿瘤微环境研究、转录组数据分析方法、数字病理图像分析等，已发表3篇一作SCI，包括Nature旗下期刊Communications Medicine和Nature Communications，并与多家医院和课题组合作共参与十余篇SCI论文的发表，包括Cell和Cancer Cell等顶级期刊。

二、研究方向

深度学习、量化金融、智慧医疗、生物信息学。

三、发表论文

[1] X. Xiao, Q. Guo, C. Cui, Y. Lin, L. Zhang, X. Ding, Q. Li, M. Wang, W. Yang*, Y. Kong*, R. Yu*. Multiplexed imaging mass cytometry reveals distinct tumor-immune microenvironments linked to immunotherapy responses in melanoma. Communications Medicine. 2022, 2(1): 131. 

[2] X. Xiao, C. Xu, W. Yang*, R. Yu*. Inconsistent prediction capability of ImmuneCells.Sig across different RNA-seq datasets. Nature Communications. 2021, 12(1): 1-3.

[3] X. Xiao, Y. Qiao, Y. Jiao, N. Fu, W. Yang, L. Wang, R. Yu*, J. Han*. Dice-XMBD: Deep learning-based cell segmentation for imaging mass cytometry. Frontiers in Genetics. 2021, 12: 721229. 

[4] S.You, S. Li, L. Zeng, J. Song,  Z. Li, W. Li, H. Ni, X. Xiao, W. Deng, H. Li, et al. Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity. Cancer Cell. 2024, 42(8): 1415-1433. 

[5] Q. Zhang, Q. Liang, R. Zhang, N. Wang, X. Xiao, J. Shao, K. Wang. Identification of SARS-CoV-2-specific T cell and its receptor. Journal of Hematology & Oncology. 2024, 17.1:15. 

[6] Y. Zhu, P. Yan, R. Wang, J. Lai, H. Tang, X. Xiao, R. Yu, X. Bao, F. Zhu, K. Wang, Y. Lu, ..., X. Chen, Q. Liang, K. Wang. Opioid-induced fragile-like regulatory T cells contribute to withdrawal. Cell. 2023, 186(3): 591-606. 

[7] Y. Lin, H. Li, X. Xiao, L. Zhang, ..., W. Yang, J. Han, R. Yu. DAISM-DNNXMBD: Highly accurate cell type proportion estimation with in silico data augmentation and deep neural networks. Patterns. 2022, 3(3): 100440.